Hench , Philip Showalter

Hench , Philip Showalter
(1896–1965) American biochemist
Born in Pittsburgh, Pennsylvania, Hench was educated at Lafayette College and the University of Pittsburgh, where he obtained his MD in 1920. He spent most of his career working at the Mayo Clinic, becoming head of the section for rheumatic diseases in 1926. Hench was also connected with the Mayo Foundation and the University of Minnesota, where he became professor of medicine in 1947.
For many years Hench had been seeking a method of treating the crippling and painful complaint of rheumatoid arthritis. He suspected that it was not a conventional microbial infection since, among other features, it was relieved by pregnancy and jaundice. Hench therefore felt it was more likely to result from a biochemical disturbance that is transiently corrected by some incidental biological change. The search, he argued, must concentrate on something patients with jaundice had in common with pregnant women. At length he was led to suppose that the antirheumatic substance might be an adrenal hormone, since temporary remissions are often induced by procedures that stimulate the adrenal cortex. Thus in 1948 he was ready to try the newly prepared ‘compound E’, later known as cortisone, of Edward Kendall on 14 patients. All showed remarkable improvement, which was reversed on withdrawing the drug.
For this development of the first steroid drug Hench shared the 1950 Nobel Prize for physiology or medicine with Kendall and Tadeus Reichstein.

Scientists. . 2011.

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  • Hench,Philip Showalter — Hench (hĕnch), Philip Showalter. 1896 1965. American physician. He shared a 1950 Nobel Prize for discoveries concerning the hormones of the adrenal cortex. * * * …   Universalium

  • Hench, Philip Showalter — ▪ American physician born Feb. 28, 1896, Pittsburgh, Pa., U.S. died March 30, 1965, Ocho Rios, Jam.  American physician who with Edward C. Kendall (Kendall, Edward Calvin) in 1948 successfully applied an adrenal hormone (later known as cortisone) …   Universalium

  • Hench, Philip Showalter — ► (1896 1965) Médico estadounidense. Fue premio Nobel de Medicina y Fisiología en 1950, compartido con E. Kendall y T. Reichstein, por el descubrimiento de la cortisona …   Enciclopedia Universal

  • Philip Showalter Hench — Born February 28, 1896(1896 02 28) Pittsburgh, Pennsylvania …   Wikipedia

  • Philip Showalter Hench — (* 28. Februar 1896 in Pittsburgh, Pennsylvania; † 30. März 1965 in Ocho Rios, Jamaika) war ein US amerikanischer Arzt. Hench studierte Medizin im Eaton Township (Pennsylvania) und promovierte 1920 an der University of Pittsburgh. Nach… …   Deutsch Wikipedia

  • Philip Showalter Hench — Saltar a navegación, búsqueda Philip Showalter Hench (Pittsburgh, Pennsylvania, Estados Unidos, 28 de febrero de 1896 Ocho Ríos, Jamaica, 30 de marzo de 1965). Realizó los estudios de Medicina y doctorado en Pennsylvania. En 1921 ingresó en la… …   Wikipedia Español

  • Philip Showalter Hench — (Pitsbugh, Pennsylvania, Estados Unidos), 28 de febrero de 1896 Ocho Ríos, Jamaica, 30 de marzo de 1965). Realizó los estudios de Medicina y doctorado en Pennsylvania. En 1921 ingresó en la Clinica Mayo, en la que permaneció toda su vida… …   Enciclopedia Universal

  • Philip Showalter Hench — Pour les articles homonymes, voir Showalter. Philip Showalter Hench (28 février 1896 à Pittsburgh, Pennsylvanie, États Unis 30 mars 1965) à Ocho Rios, Jamaïque) est un physicien américain qui a partagé avec Edward Calvin Kendall et Tadeusz… …   Wikipédia en Français

  • Hench — Philip Showalter …   Scientists

  • Hench — Hench, Philip Showalter …   Enciclopedia Universal

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